Year |
|
Winner |
Winner Work |
2013 |
|
Victor Ambros |
Discovery of microRNAs as a new class of gene regulators. |
2013 |
|
Shigekazu Nagata |
Molecular mechanisms of apoptosis and its physiology. |
2012 |
|
Steven Rosenberg |
Development of Effective Immunotherapies for Patients with Cancer. |
2012 |
|
Hiroyuki Mano |
Discovery of a lung cancer oncogene EML4-ALK and development of molecular targeted therapy. |
2011 |
|
Philip A. Beachy |
Identification of Hedgehog, a key molecule in development, and its medical applications. |
2011 |
|
Keiji Tanaka |
Discovery of proteasome and elucidation of its physiological functions. |
2010 |
|
Jules A. Hoffmann |
Discovery of insect-innate immune system and Toll receptor. |
2010 |
|
Shizuo Akira |
Elucidation of molecular mechanisms of innate immune response for microbes. |
2009 |
|
Jeffrey M. Friedman |
For the discovery of leptin and study of its physiological functions. |
2009 |
|
Kenji Kangawa |
For the discovery and clinical application of ghrelin and other novel bioactive peptides. |
2008 |
|
Fred Gage |
For the Discovery of Physiological Roles of Adult Neurogenesis in Mammalian Brain. |
2008 |
|
Shimon Sakaguchi |
For the Discovery of Regulatory T cells and Their Roles in Immunological Diseases. |
2007 |
|
Brian Druker |
For the development of a molecular-targeted therapy for chronic myelogenous leukemia. |
2007 |
|
Hiroaki Mitsuya |
For the development of anti-AIDS drugs. |
2006 |
|
Thomas A. Steitz |
The structural basis of large ribosomal subunit function and drug development. |
2005 |
|
Yoshinori Fujiyoshi |
Development of high-resolution electron cryo-microscopy for the determination of membrane protein structures. |
2004 |
|
Roger Y. Tsien |
Visualization and control of molecules within living cells. |
2003 |
|
Ronald M. Evans |
Elucidation of the molecular mechanisms of nuclear receptors that link lipid-soluble hormones and vitamins to gene expression. |
2003 |
|
Yasushi Miyashita |
Cerebral mechanisms of cognitive memory. |
2002 |
|
Barry Marshall |
Isolation and cultivation of Helicobacter pylori - pioneering work in diagnosis and treatment - |
2002 |
|
Koichi Tanaka |
Establishment and development of the living-donor liver transplantation system. |
2001 |
|
Anthony R. Hunter |
Identification of Src tyrosine kinase and functional study of cell growth and tumorgenesis. |
2001 |
|
Masatoshi Takeichi |
The discovery of cadherin and studies on the molecular mechanisms of cell-cell adhesion. |
2000 |
|
Arnold J. Levine |
p53 as a tumor suppressor gene and an important signaling molecule involved in various cellular functions. |
2000 |
|
Yusuke Nakamura |
Elucidation of various genetic diseases through human genome analysis. |
1999 |
|
Elizabeth Blackburn |
Telomere and telomerase research. |
1999 |
|
Shinya Yoshikawa |
Three Dimensional Structure of Bovine Heart Cytochrome c Oxidase and Relation with Enzyme Activity. |
1998 |
|
Judah Folkman |
|
1998 |
|
Katsuhiko Mikoshiba |
|
1997 |
|
Robert Weinberg |
|
1997 |
|
Tadatsugu Taniguchi |
|
1996 |
|
Stanley B. Prusiner |
|
1996 |
|
Shigetada Nakanishi |
|