Lasker-DeBakey Clinical Medical Research Award

Check all the winners of Lasker-DeBakey Clinical Medical Research Award.
Year Winner Winner Work
2014 Alim-Louis Benabid For the development of deep brain stimulation of the subthalamic nucleus, a surgical technique that reduces tremors and restores motor function in patients with advanced Parkinson's disease.
Mahlon DeLong For the development of deep brain stimulation of the subthalamic nucleus, a surgical technique that reduces tremors and restores motor function in patients with advanced Parkinson's disease.
2013 Graeme Clark For the development of the modern cochlear implant \u2014 a device that bestows hearing to individuals with profound deafness.
Ingeborg Hochmair For the development of the modern cochlear implant \u2014 a device that bestows hearing to individuals with profound deafness.
Blake S. Wilson For the development of the modern cochlear implant \u2014 a device that bestows hearing to individuals with profound deafness.
2012 Roy Yorke Calne For the development of liver transplantation, which has restored normal life to thousands of patients with end-stage liver disease.
Thomas Starzl For the development of liver transplantation, which has restored normal life to thousands of patients with end-stage liver disease.
2011 Tu Youyou For the discovery of artemisinin, a drug therapy for malaria that has saved millions of lives across the globe, especially in the developing world.
2010 Napoleone Ferrara For the discovery of VEGF as a major mediator of angiogenesis and the development of an effective anti-VEGF therapy for wet macular degeneration, a leading cause of blindness in the elderly.
2009 Charles Sawyers For the development of molecularly-targeted treatments for chronic myeloid leukemia, converting a fatal cancer into a manageable chronic condition.
Nicholas Lydon For the development of molecularly-targeted treatments for chronic myeloid leukemia, converting a fatal cancer into a manageable chronic condition.
Brian Druker For the development of molecularly-targeted treatments for chronic myeloid leukemia, converting a fatal cancer into a manageable chronic condition.
2008 Akira Endo For the discovery of the statins \u2014 drugs with remarkable LDL-cholesterol-lowering properties that have revolutionized the prevention and treatment of coronary heart disease.
2007 Alain Carpentier For the development of prosthetic mitral and aortic valves, which have prolonged and enhanced the lives of millions of people with heart disease
Albert Starr For the development of prosthetic mitral and aortic valves, which have prolonged and enhanced the lives of millions of people with heart disease
2006 Aaron T. Beck For the development of cognitive therapy, which has transformed the understanding and treatment of many psychiatric conditions, including depression, suicidal behavior, generalized anxiety, panic attacks, and eating disorders.
2005 Alec Jeffreys For development of two powerful technologies\u2014Southern hybridization and DNA fingerprinting\u2014that together revolutionized human genetics and forensic diagnostics.
Edwin Southern For development of two powerful technologies\u2014Southern hybridization and DNA fingerprinting\u2014that together revolutionized human genetics and forensic diagnostics.
2004 Charles Kelman For revolutionizing the surgical removal of cataracts, turning a 10-day hospital stay into an outpatient procedure, and dramatically reducing complications.
2003 Marc Feldmann For discovery of anti-TNF therapy as an effective treatment for rheumatoid arthritis and other autoimmune diseases.
Ravinder N. Maini For discovery of anti-TNF therapy as an effective treatment for rheumatoid arthritis and other autoimmune diseases.
2002 Willem Johan Kolff For the development of renal hemodialysis, which changed kidney failure from a fatal to a treatable disease, prolonging the useful lives of millions of patients.
Belding Hibbard Scribner For the development of renal hemodialysis, which changed kidney failure from a fatal to a treatable disease, prolonging the useful lives of millions of patients.
2001 Robert G. Edwards For the development of in vitro fertilization, a technological advance that has revolutionized the treatment of human infertility.
2000 Harvey J. Alter For pioneering work leading to the discovery of the virus that causes hepatitis C and the development of screening methods that reduced the risk of blood transfusion-associated hepatitis in the U.S. from 30 percent in 1970 to virtually zero in 2000.
Michael Houghton For pioneering work leading to the discovery of the virus that causes hepatitis C and the development of screening methods that reduced the risk of blood transfusion-associated hepatitis in the U.S. from 30 percent in 1970 to virtually zero in 2000.
1999 David Cushman For developing an innovative approach to drug design based on protein structure and using it to create the ACE inhibitors: powerful oral agents for the treatment of high blood pressure, heart failure, and diabetic kidney disease.
Miguel Ondetti For developing an innovative approach to drug design based on protein structure and using it to create the ACE inhibitors: powerful oral agents for the treatment of high blood pressure, heart failure, and diabetic kidney disease.
1998 Alfred G. Knudson For incisive studies in patient-oriented research that paved the way for identifying genetic alterations that cause cancer in humans and that allow for cancer diagnosis in patients at the molecular level.
Janet Rowley For incisive studies in patient-oriented research that paved the way for identifying genetic alterations that cause cancer in humans and that allow for cancer diagnosis in patients at the molecular level.
Peter Nowell For incisive studies in patient-oriented research that paved the way for identifying genetic alterations that cause cancer in humans and that allow for cancer diagnosis in patients at the molecular level.
1997 Alfred Sommer For the understanding and demonstration that low-dose vitamin A supplementation in millions of third world children can prevent death from infectious diseases as well as blindness.
1996 Porter Warren Anderson, Jr. For groundbreaking work and bold, visionary and imaginative leadership in the development and commercialization of the Hemophilus influenzae type b vaccine and bringing the vaccine to market, leading to the eradication of Hemophilus influenzae type b, typhoid, and pneumococcus.
John B. Robbins For groundbreaking work and bold, visionary and imaginative leadership in the development and commercialization of the Hemophilus influenzae type b vaccine and bringing the vaccine to market, leading to the eradication of Hemophilus influenzae type b, typhoid, and pneumococcus.
David Smith For groundbreaking work and bold, visionary and imaginative leadership in the development and commercialization of the Hemophilus influenzae type b vaccine and bringing the vaccine to market, leading to the eradication of Hemophilus influenzae type b, typhoid, and pneumococcus.
Rachel Schneerson For groundbreaking work and bold, visionary and imaginative leadership in the development and commercialization of the Hemophilus influenzae type b vaccine and bringing the vaccine to market, leading to the eradication of Hemophilus influenzae type b, typhoid, and pneumococcus.
1995 Barry Marshall For the visionary discovery that Helicobacter pylori causes peptic ulcer disease.
1994 John Allen Clements For his brilliant studies defining and describing the role of pulmonary surfactant and in developing a life-saving artificial surfactant now used in premature infants around the world.
1993 Donald Metcalf For his outstanding discovery of the colony-stimulating factors, two of which are widely used to treat patients with cancer and diseases of blood cell formation.
1992
1991 Yuet Wai Kan For his pivotal contributions to the development of human genetics, most importantly in the area of the hemoglobinopathies using recombinant DNA technology.
1990
1989 Étienne-Émile Baulieu For his contributions to the broad field of steroid hormone biosynthesis, metabolism, and receptors, and for developing RU 486, the first safe, effective contragestive medication.
1988 Vincent Dole For postulating the physiological basis of narcotic addiction and for developing methadone treatment for heroin addiction.
1987 Mogens Schou For his landmark systematic clinical trials of lithium as therapy and prophylaxis for manic depressive illness, which initiated a revolution in the treatment of mental disease.
1986 Max Essex For his pioneering studies of the feline leukemia retrovirus, and for his consistently original and widely influential studies of retroviruses in humans and other species, culminating in many of the most crucial discoveries concerning AIDS.
1986 Robert Gallo For determining that the retrovirus now known as HIV-1 is the cause of acquired immune deficiency syndrome (AIDS).
1986 Luc Montagnier For detecting a retrovirus later identified as the cause of AIDS.
1985 Bernard Fisher For his profound influence in shaping the character of modern breast cancer treatment, thus lengthening and enriching the lives of women suffering from this dread disease.
1984 Paul Lauterbur For his key theoretical and technical contributions, which made possible a completely new, versatile, and non-invasive form of medical imaging, based on nuclear magnetic resonance.
1983 F. Mason Sones For combining the techniques of cardiac catheterization and coronary artery cinematography, thus inaugurating the modern era of diagnosis and treatment of coronary artery disease.
1982 Roscoe Brady For his original and creative contributions to our understanding of a group of hereditary disorders called lipid storage diseases, and for the development of genetic counseling procedures and the initiation of possible treatment methods for these diseases.
1982 Elizabeth F. Neufeld For his original and creative contributions to our understanding of a group of hereditary disorders called lipid storage diseases, and for the development of genetic counseling procedures and the initiation of possible treatment methods for these diseases.
1981 Louis Sokoloff For developing a pioneering method which enables scientists to visualize the simultaneous biochemical activity of an entire network of neural pathways in the brain and central nervous system. This new method maps and measures their functioning, both as a whole and in localized areas, under both normal and abnormal conditions.
1980 Cyril Clarke For bringing his lively interest in heredity to bear on the genetics of the Rh antigen, thereby initiating one of the first systematic investigations in medical genetics, and for conceiving and directing epidemiological studies, basic research, and clinical investigations of Rh disease of the newborn.
1980 Ronald Finn For his dedicated and painstaking studies revealing how the unborn child is protected from the immune system of the mother, and for documenting the sequence of events leading to Rh disease in the child.
1980 Vincent J. Freda For his unrelenting drive to find a means of preventing hemolytic disease of the newborn, and for his dedicated and persistent clinical research leading to the development of the anti-Rh vaccine.
1980 John G. Gorman For his pivotal role in the development of the anti-Rh vaccine and for the scientific creativity which led him to apply to Rh disease the principle of antibody-mediated immune suppression.
1980 William Pollack For his indispensable efforts in the development of the anti-Rh vaccine, and for his immunological studies uncovering the mechanisms of Rh-incompatibility.
1979
1978 Michael Heidelberger For his elegant studies in immunochemistry, which laid the groundwork for the development of capsular purified polysaccharide vaccines for the prevention of pneumonia and meningitis.
1978 Robert Austrian For his perseverance in the development and clear demonstration of the efficacy of a purified vaccine of capsular polysaccharides in the prevention of pneumococcal diseases.
1978 Emil C. Gotschlich For his creative leadership in developing, and then demonstrating the effectiveness of a purified capsular polysaccharide vaccine in preventing meningococcal diseases.
1977 Inge G. Edler For pioneering the clinical application of ultrasound in the medical diagnosis of abnormalities of the heart\u2014probably the most important non-invasive tool for cardiac diagnosis since the electrocardiograph machine.
1977 Carl Hellmuth Hertz For pioneering the development of ultrasound technology in medicine.
1976 James Black For his design of propranolol, a drug which is a pharmacological milestone in the treatment of life-threatening cardiac diseases, angina, and severe high blood pressure.
1976 Raymond P. Ahlquist For his concept of alpha and beta receptors, which opened the door to the development of propranolol, a milestone drug in the treatment of heart diseases and severe high blood pressure.
1975 Godfrey Hounsfield For his invention of a computerized X-ray scanning system which makes it possible, for the first time, to image the brain and other soft tissue.
1975 William H. Oldendorf For his original conception of a scanning system which would be able to image soft tissue, and would thus uncover and display information that could not previously be shown by conventional radiography techniques.
1974 John Charnley For his conceptual and technical contributions to total hip joint replacement, which have opened new horizons of research and treatment in arthritis and crippling joint diseases.
1973 Paul Zoll For his development of the life-saving closed chest defibrillator and the pacemaker.
1973 William B. Kouwenhoven For his life-saving development of open and closed chest defibrillators, and for originating the technique of external cardiac massage.
1972 Min Chiu Li For their outstanding contribution to the successful chemotherapeutic treatment of gestational choriocarcinoma.
Roy Hertz For their outstanding contribution to the successful chemotherapeutic treatment of gestational choriocarcinoma.
1972 Denis Parsons Burkitt For his outstanding contribution in first identifying Burkitt's tumor.
1972 Joseph H. Burchenal For his outstanding contribution in recognizing the importance of Burkitt's tumor as a model.
1972 V. Anomah Ngu For his outstanding contribution to the expansion of the successful chemotherapeutic treatment of Burkitt's tumor.
1972 John L. Ziegler For his outstanding contribution in increasing the cure rate of Burkitt's tumor by chemotherapy.
1972 Edmund Klein For his outstanding contribution in the treatment of premalignant and malignant cancers of the skin.
1972 Emil Frei For his outstanding contribution in the application of the concept of combination chemotherapy to lymphoma and acute adult leukemia.
1972 Emil J. Freireich For his outstanding contributions in combination chemotherapy, and in supportive care of patients receiving combination chemotherapy for acute leukemia.
1972 James F. Holland For their outstanding contribution to the concept and application of combination therapy in the treatment of acute leukemia in children.
Donald Pinkel For their outstanding contribution to the concept and application of combination therapy in the treatment of acute leukemia in children.
1972 Paul P. Carbone For his outstanding contribution to the concept of combination therapy in the treatment of Hodgkin's disease.
1972 Vincent T. DeVita For his outstanding contribution to the concept of combination therapy in the treatment of Hodgkin's disease.
1972 Eugene J. Van Scott For his outstanding contribution to the concept of topical chemotherapy in the treatment of mycosis fungoides.
1972 Isaac Djerassi For his outstanding contribution in the supportive care, by platelet transfusion, of patients receiving intensive chemotherapy.
1972 Gordon Zubrod Special Award: For his leadership in expanding the frontiers of cancer chemotherapy.
1971 Edward D. Freis For his demonstration of the life-saving effectiveness of drugs in the treatment of moderate hypertension.
1970 Robert A. Good For his uniquely important contributions to our understanding of the mechanism of immunity.
1969 George Cotzias For his demonstration of the effectiveness of large daily dosages of L-DOPA in the treatment of Parkinson's disease.
1968 John Heysham Gibbon For designing and developing the heart-lung machine.
1967 Robert A. Phillips For his enormous contribution to the understanding of the mechanism of death in cholera, and the development of a life-saving method of treating it.
1966 Sidney Farber For his original use of aminopterin and methotrexate in the control of acute childhood leukemia, and for his constant leadership in the search for chemical agents against cancer.
1965 Albert Sabin For the development of a live, oral poliovirus vaccine.
1964 Nathan S. Kline For the introduction and use of iproniazid in the treatment of severe depression.
1963 Michael E. DeBakey For his brilliant leadership and professional accomplishments, which were responsible in a large measure for inaugurating a new era in cardiovascular surgery.
1963 Charles Brenton Huggins For his role as a catalyst in modern endocrine studies of tumor control in animals and humans.
1962 Joseph Edward Smadel For outstanding contributions to the understanding, diagnosis, and treatment of virus and rickettsial diseases, including the demonstration of the efficacy of chloramphenicol as a cure for rickettsial infections\u2014typhoid fever and epidemic and scrub typhus.
1961
1960 Karl Paul Link Joint award for pioneering the development and use of anticoagulant drugs.
Irving Wright Joint award for pioneering the development and use of anticoagulant drugs.
Edgar Allen Joint award for pioneering the development and use of anticoagulant drugs.
1959 John Holmes Dingle For outstanding studies which have added significantly to our knowledge and ability to control acute respiratory diseases.
1959 Gilbert Dalldorf For his demonstration of the ability of one virus to modify the course of infection by another and for his discovery of Coxsackie virus by a unique and broadly applicable technique.
1959 Robert E. Gross For distinguished achievement: performing the first successful operation on an inborn cardiovascular defect.
1958 Robert Wallace Wilkins For distinguished contributions to the control of heart and blood vessel diseases through outstanding investigations into the causes, diagnosis and treatment of hypertension.
1957 Richard Shope For outstanding contributions to the better understanding of infectious diseases in animals and man and his discovery of new microbiological principles of far-reaching importance.
1957 Nathan S. Kline For his demonstrations of the value of Rauwolfia derivatives, especially reserpine, in the treatment of mental and nervous disorders.
1957 Robert Noce For his studies of reserpine and its uses among the mentally ill and among mental defectives.
1957 Henri Laborit For his extensive studies of surgical shock and post-operative illness which resulted in the first application of chlorpromazine as a therapeutic agent.
1957 Pierre Deniker For his introduction of chlorpromazine into psychiatry, and for his demonstration that a medication can influence the clinical course of the major psychoses.
1957 Heinz Lehmann For his demonstrations of the clinical uses of chlorpromazine in the treatment of mental disorders.
1957 Rustom Jal Vakil For his brilliant and systematic studies on Rauwolfia in hypertension.
1956 Jonas Salk For developing a safe and effective vaccine against poliomyelitis.
1956 Louis N. Katz For his contribution to cardiovascular research and his advancement of the thesis that experimental atherosclerosis is basically a metabolic disease that is preventable and reversible.
1956 V. Everett Kinsey For his outstanding work as coordinator of the National Cooperative Study of Retrolental Fibroplasia.
1956 Arnall Patz For his original, well-controlled studies in the cause and prevention of retrolental fibroplasia.
1955 Morley Cohen Joint award for advances in cardiac surgery, making possible more direct and safer approaches to the heart.
Herbert Warden Joint award for advances in cardiac surgery, making possible more direct and safer approaches to the heart.
Richard Varco Joint award for advances in cardiac surgery, making possible more direct and safer approaches to the heart.
C. Walton Lillehei Joint award for advances in cardiac surgery, making possible more direct and safer approaches to the heart.
1955 Edward H. Robitzek Joint award for establishing the great efficacy of isoniazid drugs in the treatment of tuberculous meningitis and generalized miliary tuberculosis.
Bristol-Myers Squibb Joint award for establishing the great efficacy of isoniazid drugs in the treatment of tuberculous meningitis and generalized miliary tuberculosis.
Hoffmann-La Roche Joint award for establishing the great efficacy of isoniazid drugs in the treatment of tuberculous meningitis and generalized miliary tuberculosis.
Irving Selikoff Joint award for establishing the great efficacy of isoniazid drugs in the treatment of tuberculous meningitis and generalized miliary tuberculosis.
Carl Muschenheim Joint award for establishing the great efficacy of isoniazid drugs in the treatment of tuberculous meningitis and generalized miliary tuberculosis.
Walsh McDermott Joint award for establishing the great efficacy of isoniazid drugs in the treatment of tuberculous meningitis and generalized miliary tuberculosis.
1954 Alfred Blalock Joint award for distinguished contributions to cardiovascular surgery and knowledge.
Robert E. Gross Joint award for distinguished contributions to cardiovascular surgery and knowledge.
Helen B. Taussig Joint award for distinguished contributions to cardiovascular surgery and knowledge.
1953 Paul Dudley White For distinguished achievement in the pathology, diagnosis and treatment of heart disease.
1952 Conrad Elvehjem For distinguished contributions to biochemical and nutrition research.
1952 Henry Trendley Dean Joint award for leadership in the development of community-wide fluoridation programs.
Frederick McKay Joint award for leadership in the development of community-wide fluoridation programs.
1951 Catherine Macfarlane Joint award for their pioneer work in developing cancer detection clinics for the discovery of early cancer or precancerous lesions in presumably healthy people.
Elise L'Esperance Joint award for their pioneer work in developing cancer detection clinics for the discovery of early cancer or precancerous lesions in presumably healthy people.
1951 William Gordon Lennox Joint award for their research in epilepsy.
Frederic A. Gibbs Joint award for their research in epilepsy.
1950 Georgios Papanikolaou For outstanding contributions to the early diagnosis of cancer through cytological methods.
1949 Edward Calvin Kendall Joint award for their chemical physiological and clinical studies of adrenal hormones which culminated in the development of the use of cortisone in rheumatic disease therapy.
Philip Showalter Hench Joint award for their chemical physiological and clinical studies of adrenal hormones which culminated in the development of the use of cortisone in rheumatic disease therapy.
1949 Max Theiler For distinguished experimental work leading directly to the production of two effective vaccines against yellow fever.
1948
1947
1946 John Friend Mahoney For distinguished service as a pioneer in the treatment of syphilis with penicillin.
1946 Karl Landsteiner Joint award for the discovery of the Rh factor and its significance as a cause of maternal, prenatal and neonatal morbidity and mortality.
Alexander S. Wiener Joint award for the discovery of the Rh factor and its significance as a cause of maternal, prenatal and neonatal morbidity and mortality.
Philip Levine Joint award for the discovery of the Rh factor and its significance as a cause of maternal, prenatal and neonatal morbidity and mortality.