2013 Breakthrough Prize in Life Sciences

Cornelia Bargmann

(For the genetics of neural circuits and behavior, and synaptic guidepost molecules.)

David Botstein

(For linkage mapping of Mendelian disease in humans using DNA polymorphisms.)

Lewis C. Cantley

(For the discovery of PI 3-Kinase and its role in cancer metabolism.)

Hans Clevers

(For describing the role of Wnt signaling in tissue stem cells and cancer.)

Titia de Lange

(For research on telomeres, illuminating how they protect chromosome ends and their role in genome instability in cancer.)

Napoleone Ferrara

(For discoveries in the mechanisms of angiogenesis that led to therapies for cancer and eye diseases.)

Eric Lander

(For the discovery of general principles for identifying human disease genes, and enabling their application to medicine through the creation and analysis of genetic, physical and sequence maps of the human genome.)

Charles Sawyers

(For cancer genes and targeted therapy.)

Robert Weinberg

(For characterization of human cancer genes.)

Shinya Yamanaka

(For induced pluripotent stem cells.)

Bert Vogelstein

(For cancer genomics and tumor suppressor genes.)