Awards & Winners

Alexander Varshavsky

Profession Chemist
Alexander Jacob Varshavsky is a Russian-American biochemist, noted for his discovery of the N-end rule of ubiquitination. A native of Moscow, he is currently researching at Caltech. Varshavsky provided an original approach to killing cancer cells, proffering the idea of a targeted molecular device that could enter a cell, examine it for DNA deletions specific to cancer and killing it if it meets the right profile. " involves, in a nutshell, the finding of a genuine Achilles' heel of cancer cells, i.e. their potentially vulnerable feature that won't change during tumor progression," said Varshavsky. The approach termed deletion-specific targeting, employs HDs as the targets of cancer therapy. "In contrast to other attributes of cancer cells, their HDs are immutable markers. If the DST strategy can be implemented in a clinical setting, it may prove to be both curative and free of side effects."

Awards by Alexander Varshavsky

Check all the awards nominated and won by Alexander Varshavsky.


Louisa Gross Horwitz Prize
(For his research on ubiquitination.)
E. B. Wilson Medal


Massry Prize
Wolf Prize in Medicine
(For the discovery of the ubiquitin system of intracellular protein degradation and the crucial functions of this system in cellular regulation.)


Albert Lasker Award for Basic Medical Research
(For the discovery and the recognition of the significance of the ubiquitin system of regulated protein degradation, a fundamental process that influences vital cellular events, including the cell cycle, malignant transformation, and responses to inflammation and immunity)


Gairdner Foundation International Award
(For the discovery of the ubiquitin system of intracellular protein degradation and its many functions in the cell.)