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Date of Birth
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01-July-1941
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Place of Birth
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New Haven
(Connecticut, United States of America, New Haven County, Area code 203, Area code 475)
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Nationality
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United States of America
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Also know as
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Alfred Gilman, Alfred G Gilman
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Alfred Goodman Gilman is an American pharmacologist and biochemist. He shared the 1994 Nobel Prize in Physiology or Medicine with Martin Rodbell for their discoveries regarding G-proteins.
G-proteins are a vital intermediary between the extracellular activation of receptors on the cell membrane and actions within the cell. Rodbell had shown in the 1960s that GTP was involved in cell signaling. It was Gilman who actually discovered the proteins that interacted with the GTP to initiate signalling cascades within the cell.
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