Awards & Winners

Mark Ptashne

Date of Birth 05-June-1940
Place of Birth Chicago
(Illinois, United States of America, Chicago metropolitan area, Area code 872)
Nationality United States of America
Also know as Mark S. Ptashne, Mark Stephen Ptashne
Mark Ptashne is a molecular biologist and violinist. He currently holds the Ludwig Chair of Molecular Biology at Memorial Sloan–Kettering Cancer Center in New York. He was the first scientist to demonstrate specific binding between protein and DNA, and his lifelong work has been the elucidation of the molecular mechanisms of switch between lytic and lysogenic lifecyle of bacteriophage lambda, as well as how the yeast transcriptional activator Gal4 works. He was the originator of the "ball and stick" model of transcription factor function, demonstrating in bacteria and in yeast that they typically consist of separable regions that mediate DNA binding and interaction with transcriptional activators or repressors. In 1980 he cofounded Genetics Institute, Inc. with Thomas Maniatis, which was acquired by Wyeth 1996. In 1985, he was awarded the Louisa Gross Horwitz Prize from Columbia University. He won the Albert Lasker Award for Basic Medical Research in 1997, and the Massry Prize from the Keck School of Medicine, University of Southern California in 1998. He has written popular books for a wider scientific audience, including his book Genes and Signals.

Awards by Mark Ptashne

Check all the awards nominated and won by Mark Ptashne.


Massry Prize
(In the field of Regulation of Transcription.)
Albert Lasker Award for Basic Medical Research
(For elegant and incisive discoveries leading to the understanding of how regulatory proteins control the transcription of genes.)


Gairdner Foundation International Award
(For their many contributions in the field of molecular genetics, especially in the field of gene regulation.)
Louisa Gross Horwitz Prize


NAS Award in Molecular Biology
(For his outstanding contributions to our understanding of gene regulation through the studies of the virus Lambda.)